{"id":2117,"date":"2025-08-26T16:42:27","date_gmt":"2025-08-26T14:42:27","guid":{"rendered":"https:\/\/admixtio.com\/the-new-frontier-of-fermentation-postbiotic-bioactives-for-skin-and-gut\/"},"modified":"2025-08-26T16:42:27","modified_gmt":"2025-08-26T14:42:27","slug":"the-new-frontier-of-fermentation-postbiotic-bioactives-for-skin-and-gut","status":"publish","type":"post","link":"https:\/\/admixtio.com\/en\/the-new-frontier-of-fermentation-postbiotic-bioactives-for-skin-and-gut\/","title":{"rendered":"The New Frontier of Fermentation: Postbiotic Bioactives for Skin and Gut"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2109 aligncenter\" src=\"https:\/\/admixtio.com\/wp-content\/uploads\/2025\/08\/postbiotics2-300x200.webp\" alt=\"postbiotics\" width=\"476\" height=\"317\" \/> \u00a0<\/p>\n<div class=\"flex flex-1 grow basis-auto flex-col overflow-hidden\">\n<div class=\"relative h-full\">\n<div class=\"flex h-full flex-col overflow-y-auto [scrollbar-gutter:stable]\">\n<div class=\"@thread-xl\/thread:pt-header-height mt-1.5 flex flex-col text-sm md:pb-9\">\n<article class=\"text-token-text-primary w-full\" dir=\"auto\" data-testid=\"conversation-turn-4\" data-scroll-anchor=\"true\">\n<div class=\"text-base my-auto mx-auto py-5 px-6\">\n<div class=\"mx-auto flex flex-1 text-base gap-4 md:gap-5 lg:gap-6 md:max-w-3xl group\/turn-messages focus-visible:outline-hidden\" tabindex=\"-1\">\n<div class=\"group\/conversation-turn relative flex w-full min-w-0 flex-col agent-turn @xs\/thread:px-0 @sm\/thread:px-1.5 @md\/thread:px-4\">\n<div class=\"relative flex-col gap-1 md:gap-3\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-5\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"a1feac6c-23ac-4f7d-b111-a0bd8af53971\" data-message-model-slug=\"gpt-4o\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[3px]\">\u00a0<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"isolate w-full basis-auto has-data-has-thread-error:pt-2 has-data-has-thread-error:[box-shadow:var(--sharp-edge-bottom-shadow)] md:border-transparent md:pt-0 dark:border-white\/20 md:dark:border-transparent flex flex-col\">\n<div class=\"text-base mx-auto px-3 md:px-4 w-full md:px-5 lg:px-4 xl:px-5\">\n<div class=\"mx-auto flex flex-1 text-base gap-4 md:gap-5 lg:gap-6 md:max-w-3xl\">\n<div class=\"relative z-1 flex max-w-full flex-1 flex-col h-full max-xs:[--force-hide-label:none]\" aria-haspopup=\"dialog\" aria-expanded=\"false\" aria-controls=\"radix-:R7khioukkt995j5:\" data-state=\"closed\">\n<form class=\"w-full [view-transition-name:var(--vt-composer)]\" data-type=\"unified-composer\">\n<div class=\"border-token-border-xlight flex w-full cursor-text flex-col items-center justify-center rounded-[28px] border bg-clip-padding contain-inline-size overflow-clip shadow-sm sm:shadow-lg dark:shadow-none! bg-token-main-surface-primary dark:bg-[#303030]\">\n<div class=\"relative flex w-full items-end px-3 py-3\">\n<p data-start=\"190\" data-end=\"549\">In a world where skin and gut health are increasingly interconnected, concepts like <strong data-start=\"274\" data-end=\"288\">microbiota<\/strong>, <strong data-start=\"290\" data-end=\"306\">skin barrier<\/strong>, or <strong data-start=\"311\" data-end=\"334\">intestinal immunity<\/strong> have become common language for the conscious consumer. This shift has driven a new wave of innovation centered on <strong data-start=\"450\" data-end=\"465\">postbiotics<\/strong>\u2014fermented ingredients that offer tangible benefits in both cosmetics and nutrition.<\/p>\n<p data-start=\"551\" data-end=\"767\">At <strong data-start=\"554\" data-end=\"566\">Admixtio<\/strong>, we support brands that want to go beyond trends and formulate with <strong data-start=\"635\" data-end=\"696\">functional, stable, and evidence-based active ingredients<\/strong>. Among these, postbiotics stand out as a category of growing interest.<\/p>\n<h2 data-start=\"774\" data-end=\"801\"><strong>What is a postbiotic?<\/strong><\/h2>\n<p data-start=\"803\" data-end=\"950\">According to the definition established by the <strong data-start=\"850\" data-end=\"928\">ISAPP (International Scientific Association for Probiotics and Prebiotics)<\/strong>, a <strong data-start=\"932\" data-end=\"946\">postbiotic<\/strong> is:<\/p>\n<p data-start=\"803\" data-end=\"950\">\u201cA preparation of inanimate microorganisms and\/or their components that confers a health benefit on the host.\u201d<\/p>\n<p data-start=\"1066\" data-end=\"1080\">This includes:<\/p>\n<ul data-start=\"1081\" data-end=\"1264\">\n<li data-start=\"1081\" data-end=\"1180\">\n<p data-start=\"1083\" data-end=\"1180\">Bioactive metabolites generated during fermentation (short-chain fatty acids, peptides, enzymes\u2026)<\/p>\n<\/li>\n<li data-start=\"1181\" data-end=\"1264\">\n<p data-start=\"1183\" data-end=\"1264\">Cell fragments, bacterial wall, or other by-products from the inactivated culture<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1266\" data-end=\"1467\">Unlike probiotics or prebiotics, <strong data-start=\"1299\" data-end=\"1338\">postbiotics do not need to be alive<\/strong> to be effective, which makes them safer, more stable, and easier to integrate into cosmetic formulations or dietary supplements.<\/p>\n<h2 data-start=\"1474\" data-end=\"1503\"><strong>Benefits of Postbiotics<\/strong><\/h2>\n<h3 data-start=\"1505\" data-end=\"1530\">In natural cosmetics:<\/h3>\n<ul data-start=\"1531\" data-end=\"1791\">\n<li data-start=\"1531\" data-end=\"1570\">\n<p data-start=\"1533\" data-end=\"1570\">Reinforcement of the <strong data-start=\"1554\" data-end=\"1570\">skin barrier<\/strong><\/p>\n<\/li>\n<li data-start=\"1571\" data-end=\"1610\">\n<p data-start=\"1573\" data-end=\"1610\">Regulation of the <strong data-start=\"1591\" data-end=\"1610\">skin microbiome<\/strong><\/p>\n<\/li>\n<li data-start=\"1611\" data-end=\"1652\">\n<p data-start=\"1613\" data-end=\"1652\">Improved <strong data-start=\"1622\" data-end=\"1635\">hydration<\/strong> and <strong data-start=\"1640\" data-end=\"1652\">radiance<\/strong><\/p>\n<\/li>\n<li data-start=\"1653\" data-end=\"1719\">\n<p data-start=\"1655\" data-end=\"1719\"><strong data-start=\"1655\" data-end=\"1667\">Soothing<\/strong> and <strong data-start=\"1672\" data-end=\"1693\">anti-inflammatory<\/strong> effect for sensitive skin<\/p>\n<\/li>\n<li data-start=\"1720\" data-end=\"1791\">\n<p data-start=\"1722\" data-end=\"1791\">Stimulation of <strong data-start=\"1737\" data-end=\"1749\">collagen<\/strong> and <strong data-start=\"1754\" data-end=\"1778\">antioxidant activity<\/strong> (anti-aging)<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1793\" data-end=\"1938\">Postbiotics are used in products targeting <strong data-start=\"1836\" data-end=\"1874\">sensitive, aging, or reactive skin<\/strong>, especially in formats like serums, toners, or light emulsions.<\/p>\n<h3 data-start=\"1940\" data-end=\"1968\">In functional nutrition:<\/h3>\n<ul data-start=\"1969\" data-end=\"2191\">\n<li data-start=\"1969\" data-end=\"2030\">\n<p data-start=\"1971\" data-end=\"2030\">Modulation of the <strong data-start=\"1989\" data-end=\"2030\">gut-associated lymphoid tissue (GALT)<\/strong><\/p>\n<\/li>\n<li data-start=\"2031\" data-end=\"2091\">\n<p data-start=\"2033\" data-end=\"2091\">Improved <strong data-start=\"2042\" data-end=\"2055\">digestion<\/strong> and <strong data-start=\"2060\" data-end=\"2091\">intestinal mucosa integrity<\/strong><\/p>\n<\/li>\n<li data-start=\"2092\" data-end=\"2132\">\n<p data-start=\"2094\" data-end=\"2132\">Reduction of <strong data-start=\"2107\" data-end=\"2132\">systemic inflammation<\/strong><\/p>\n<\/li>\n<li data-start=\"2133\" data-end=\"2191\">\n<p data-start=\"2135\" data-end=\"2191\">Synergistic potential with <strong data-start=\"2162\" data-end=\"2191\">probiotics and prebiotics<\/strong><\/p>\n<\/li>\n<\/ul>\n<p data-start=\"2193\" data-end=\"2304\">They are widely used in oral supplements focused on <strong data-start=\"2245\" data-end=\"2281\">gut health, immunity, metabolism<\/strong>, and general wellness.<\/p>\n<h2 data-start=\"2311\" data-end=\"2361\"><strong>Types of Postbiotics and Plant-Based Origins<\/strong><\/h2>\n<p data-start=\"2363\" data-end=\"2424\">Many postbiotics result from fermentation processes based on:<\/p>\n<ul data-start=\"2426\" data-end=\"2690\">\n<li data-start=\"2426\" data-end=\"2487\">\n<p data-start=\"2428\" data-end=\"2487\"><strong data-start=\"2428\" data-end=\"2446\">Plant extracts<\/strong>: carrot, beetroot, kale, green tea, etc.<\/p>\n<\/li>\n<li data-start=\"2488\" data-end=\"2557\">\n<p data-start=\"2490\" data-end=\"2557\"><strong data-start=\"2490\" data-end=\"2515\">Agri-food by-products<\/strong>: grape pomace, olive pulp, coffee grounds<\/p>\n<\/li>\n<li data-start=\"2558\" data-end=\"2628\">\n<p data-start=\"2560\" data-end=\"2628\"><strong data-start=\"2560\" data-end=\"2582\">Grains and legumes<\/strong>: rice, barley, quinoa, fermented soy (tempeh)<\/p>\n<\/li>\n<li data-start=\"2629\" data-end=\"2690\">\n<p data-start=\"2631\" data-end=\"2690\"><strong data-start=\"2631\" data-end=\"2661\">Functional fungi and algae<\/strong>: kombucha, reishi, shiitake\u2026<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"2692\" data-end=\"2877\">Through <strong data-start=\"2700\" data-end=\"2727\">controlled fermentation<\/strong>, the <strong data-start=\"2733\" data-end=\"2772\">bioavailability of active compounds<\/strong> is enhanced, and <strong data-start=\"2790\" data-end=\"2817\">new bioactive molecules<\/strong> are generated that are not present in the original extract.<\/p>\n<h2 data-start=\"2884\" data-end=\"2926\"><strong>Advantages for Formulators and Brands<\/strong><\/h2>\n<ul data-start=\"2928\" data-end=\"3200\">\n<li data-start=\"2928\" data-end=\"2985\">\n<p data-start=\"2930\" data-end=\"2985\"><strong data-start=\"2930\" data-end=\"2948\">High stability<\/strong> under temperature, oxidation, and pH<\/p>\n<\/li>\n<li data-start=\"2986\" data-end=\"3065\">\n<p data-start=\"2988\" data-end=\"3065\"><strong data-start=\"2988\" data-end=\"3003\">Clean label<\/strong>: safe, well-regulated ingredients without live microorganisms<\/p>\n<\/li>\n<li data-start=\"3066\" data-end=\"3131\">\n<p data-start=\"3068\" data-end=\"3131\"><strong data-start=\"3068\" data-end=\"3097\">Microbiome-friendly trend<\/strong>: aligned with the modern consumer<\/p>\n<\/li>\n<li data-start=\"3132\" data-end=\"3200\">\n<p data-start=\"3134\" data-end=\"3200\">Scientifically backed ingredients with an <strong data-start=\"3176\" data-end=\"3200\">innovative narrative<\/strong><\/p>\n<\/li>\n<\/ul>\n<h2 data-start=\"3207\" data-end=\"3235\"><strong>How Can Admixtio Help?<\/strong><\/h2>\n<p data-start=\"3237\" data-end=\"3318\">At <strong data-start=\"3240\" data-end=\"3252\">Admixtio<\/strong>, we provide both <strong data-start=\"3270\" data-end=\"3305\">technical and strategic support<\/strong> to help you:<\/p>\n<ul data-start=\"3320\" data-end=\"3606\">\n<li data-start=\"3320\" data-end=\"3379\">\n<p data-start=\"3322\" data-end=\"3379\">Identify postbiotic ingredients with proven functionality<\/p>\n<\/li>\n<li data-start=\"3380\" data-end=\"3455\">\n<p data-start=\"3382\" data-end=\"3455\">Integrate them into <strong data-start=\"3402\" data-end=\"3429\">cosmetic or nutritional<\/strong> formulations with purpose<\/p>\n<\/li>\n<li data-start=\"3456\" data-end=\"3536\">\n<p data-start=\"3458\" data-end=\"3536\">Assess their properties depending on skin type, application, or target benefit<\/p>\n<\/li>\n<li data-start=\"3537\" data-end=\"3606\">\n<p data-start=\"3539\" data-end=\"3606\">Build an authentic brand story rooted in <strong data-start=\"3580\" data-end=\"3606\">science and innovation<\/strong><\/p>\n<\/li>\n<\/ul>\n<h2 data-start=\"3613\" data-end=\"3659\"><strong>Recommended References and Web Resources<\/strong><\/h2>\n<ul data-start=\"3661\" data-end=\"4434\">\n<li data-start=\"3661\" data-end=\"3768\">\n<p data-start=\"3664\" data-end=\"3768\">ISAPP \u2013 International Scientific Association for Probiotics and Prebiotics<br data-start=\"3738\" data-end=\"3741\" \/><a class=\"decorated-link\" href=\"https:\/\/isappscience.org\" target=\"_new\" rel=\"noopener\" data-start=\"3744\" data-end=\"3768\">https:\/\/isappscience.org<\/a><\/p>\n<\/li>\n<li data-start=\"3770\" data-end=\"3983\">\n<p data-start=\"3773\" data-end=\"3983\">Salminen, S. et al. (2021). \u201cISAPP consensus statement on the definition and scope of postbiotics.\u201d <em data-start=\"3873\" data-end=\"3919\">Nature Reviews Gastroenterology &amp; Hepatology<\/em>, 18(9), 649\u2013667<br data-start=\"3935\" data-end=\"3938\" \/><a class=\"decorated-link\" href=\"https:\/\/doi.org\/10.1038\/s41575-021-00440-6\" target=\"_new\" rel=\"noopener\" data-start=\"3941\" data-end=\"3983\">https:\/\/doi.org\/10.1038\/s41575-021-00440-6<\/a><\/p>\n<\/li>\n<li data-start=\"3985\" data-end=\"4180\">\n<p data-start=\"3988\" data-end=\"4180\">Villarreal-Soto, S. A. et al. (2020). \u201cPostbiotics: mechanisms and functional applications.\u201d <em data-start=\"4081\" data-end=\"4118\">Trends in Food Science &amp; Technology<\/em>, 102, 117\u2013132<br data-start=\"4132\" data-end=\"4135\" \/><a class=\"decorated-link\" href=\"https:\/\/doi.org\/10.1016\/j.tifs.2020.05.018\" target=\"_new\" rel=\"noopener\" data-start=\"4138\" data-end=\"4180\">https:\/\/doi.org\/10.1016\/j.tifs.2020.05.018<\/a><\/p>\n<\/li>\n<li data-start=\"4182\" data-end=\"4310\">\n<p data-start=\"4185\" data-end=\"4310\"><em data-start=\"4185\" data-end=\"4209\">Cosmetics &amp; Toiletries<\/em> \u2013 \u201cPostbiotic Skin Care: What It Is and Why It Matters\u201d<br data-start=\"4265\" data-end=\"4268\" \/><a class=\"decorated-link\" href=\"https:\/\/www.cosmeticsandtoiletries.com\/\" target=\"_new\" rel=\"noopener\" data-start=\"4271\" data-end=\"4310\">https:\/\/www.cosmeticsandtoiletries.com\/<\/a><\/p>\n<\/li>\n<li data-start=\"4312\" data-end=\"4434\">\n<p data-start=\"4315\" data-end=\"4434\"><em data-start=\"4315\" data-end=\"4333\">NutraIngredients<\/em> \u2013 \u201cPostbiotics: the new frontier for gut health and immunity\u201d<br data-start=\"4395\" data-end=\"4398\" \/><a class=\"decorated-link\" href=\"https:\/\/www.nutraingredients.com\/\" target=\"_new\" rel=\"noopener\" data-start=\"4401\" data-end=\"4434\">https:\/\/www.nutraingredients.com\/<\/a><\/p>\n<\/li>\n<\/ul>\n<h2 data-start=\"4441\" data-end=\"4495\"><strong>Interested in working with postbiotic ingredients?<\/strong><\/h2>\n<p data-start=\"4497\" data-end=\"4608\"><strong data-start=\"4497\" data-end=\"4512\"><a href=\"https:\/\/admixtio.com\/en\/contact\/\">Contact us<\/a>.<\/strong> At Admixtio, we help you turn scientific sustainability into <strong data-start=\"4574\" data-end=\"4607\">real and effective innovation<\/strong>.<\/p>\n<\/div>\n<\/div>\n<\/form>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0 \u00a0 In a world where skin and gut health are increasingly interconnected, concepts like microbiota, skin barrier, or intestinal immunity have become common language for the conscious consumer. This shift has driven a new wave of innovation centered on postbiotics\u2014fermented ingredients that offer tangible benefits in both cosmetics and nutrition. At Admixtio, we support [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":2111,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"categories":[23],"tags":[],"class_list":["post-2117","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-personal-care"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The New Frontier of Fermentation: Postbiotic Bioactives for Skin and Gut<\/title>\n<meta name=\"description\" content=\"In a world where skin and gut health are increasingly interconnected, concepts like microbiota, skin barrier, or intestinal immunity have become common language for the conscious consumer. 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